Scientific Publications
Brandt E, Keskin M, Räisänen IT, Tervahartiala T, Mäkitie A, Harmankaya İ, Karaçetin D, Hagström J, Rautava J, Sorsa T. Induction of Collagenolytic MMP-8 and -9 Tissue Destruction Cascade in Mouth by Head and Neck Cancer Radiotherapy: A Cohort Study. Biomedicines. 2023 Dec 21;12(1):27. doi: 10.3390/biomedicines12010027. PMID: 38275388; PMCID: PMC10813307.
Brandt E, Keskin M, Räisänen IT, Tervahartiala T, Mäkitie A, Harmankaya İ, Karaçetin D, Hagström J, Rautava J, Sorsa T. Induction of Collagenolytic MMP-8 and -9 Tissue Destruction Cascade in Mouth by Head and Neck Cancer Radiotherapy: A Cohort Study. Biomedicines. 2023 Dec 21;12(1):27. doi: 10.3390/biomedicines12010027. PMID: 38275388; PMCID: PMC10813307.
Brandt E, Keskin M, Tervahartiala T, Yılmaz M, Harmankaya İ, Karaçetin D, İpek T, Gürsoy UK, Rautava J, Gupta S, Hagström J, Räisänen IT, Sorsa T. Radiotherapy Increases aMMP-8-Levels and Neutrophil/Lymphocyte Ratio Rapidly in Head and Neck Cancer Patients: A Pilot Study. Cancer Control. 2023 Jan-Dec;30:10732748231163653. doi: 10.1177/10732748231163653. PMID: 37092545; PMCID: PMC10134104.
Kompuinen J, Keskin M, Yilmaz D, Gürsoy M, Gürsoy UK. Human β-Defensins in Diagnosis of Head and Neck Cancers. Cells. 2023 Mar 7;12(6):830. doi: 10.3390/cells12060830. PMID: 36980171; PMCID: PMC10047923.
Keskin M, Rintamarttunen J, Gülçiçek E, Räisänen IT, Gupta S, Tervahartiala T, Pätilä T, Sorsa T. A Comparative Analysis of Treatment-Related Changes in the Diagnostic Biomarker Active Metalloproteinase-8 Levels in Patients with Periodontitis. Diagnostics (Basel). 2023 Feb 27;13(5):903. doi: 10.3390/diagnostics13050903. PMID: 36900047; PMCID: PMC10001139.
Keskin M, Kompuinen J, Harmankaya İ, Karaçetin D, Nissilä V, Gürsoy M, Sorsa T, Gürsoy UK. Oral Cavity Calprotectin and Lactoferrin Levels in Relation to Radiotherapy. Curr Issues Mol Biol. 2022 Sep 26;44(10):4439-4446. doi: 10.3390/cimb44100304. PMID: 36286019; PMCID: PMC9600558.
Sorsa T, Nwhator SO, Sakellari D, Grigoriadis A, Umeizudike KA, Brandt E, Keskin M, Tervahartiala T, Pärnänen P, Gupta S, Mohindra R, Bostanci N, Buduneli N, Räisänen IT. aMMP-8 Oral Fluid PoC Test in Relation to Oral and Systemic Diseases. Front Oral Health. 2022 Jun 10;3:897115. doi: 10.3389/froh.2022.897115. PMID: 35757444; PMCID: PMC9226345.
Keskin M, Lähteenmäki H, Rathnayake N, Räisänen IT, Tervahartiala T, Pärnänen P, Şenışık AM, Karaçetin D, Yentek Balkanay A, Heikkilä P, Hagström J, Rautava J, Haglund C, Gursoy UK, Silbereisen A, Bostanci N, Sorsa T. Active matrix metalloproteinase-8 and interleukin-6 detect periodontal degeneration caused by radiotherapy of head and neck cancer: a pilot study. Expert Rev Proteomics. 2020 Oct;17(10):777-784. doi: 10.1080/14789450.2020.1858056. Epub 2021 Jan 7. PMID: 33406924.
Keskin M, Zeidán-Chuliá F, Gursoy M, Könönen E, Rautava J, Gursoy UK. Two Cheers for Crohn's Disease and Periodontitis: Beta-Defensin-2 as an Actionable Target to Intervene on Two Clinically Distinct Diseases. OMICS. 2015 Aug;19(8):443-50. doi: 10.1089/omi.2015.0077. Epub 2015 Jul 14. PMID: 26171729.
Keskin M, Könönen E, Söderling E, Isik G, Firatli E, Uitto VJ, Gürsoy UK. Increased proliferation and decreased membrane permeability as defense mechanisms of Fusobacterium nucleatum against human neutrophilic peptide-1. Anaerobe. 2014 Dec;30:35-40. doi: 10.1016/j.anaerobe.2014.08.001. Epub 2014 Aug 12. PMID: 25132418.
Zeidán-Chuliá F, Keskin M, Könönen E, Uitto VJ, Söderling E, Moreira JC, Gürsoy UK. Antibacterial and antigelatinolytic effects of Satureja hortensis L. essential oil on epithelial cells exposed to Fusobacterium nucleatum. J Med Food. 2015 Apr;18(4):503-6. doi: 10.1089/jmf.2013.0052. Epub 2014 Jan 9. PMID: 24404975.
Marttinen AM, Haukioja AL, Keskin M, Söderling EM. Effects of Lactobacillus reuteri PTA 5289 and L. paracasei DSMZ16671 on the adhesion and biofilm formation of Streptococcus mutans. Curr Microbiol. 2013 Aug;67(2):193-9. doi: 10.1007/s00284-013-0352-3. Epub 2013 Mar 17. PMID: 23503788.
Keskin, Mutlu. "A comparative analysis of biofilm characteristics of Dual-Species periodontopathogenic biofilm based on fusobacterium nucleatum and the Dual-Species biofilm response in the presence of antimicrobial peptide." (2020).
Keskin, Mutlu. "Effect of D-Ribose on Fusobacterium Nucleatum Planktonic Proliferation and Biofilm Maturation." Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13.3 (2022): 379-384.